How and When Should Newborn Screening Be Carried Out? - Trinitron

 

Universal Newborn Screening is a set of simple tests administered to newborn babies within 24 to 72 hours of birth, which helps to detect congenital metabolic disorders and conditions. Without these tests, it is possible that permanent and irreversible damage may have occurred before any clinical signs are evident. By having these Newborn Screening Kit, it becomes possible to provide immediate treatment and avoid further complications. It is important to note that these tests are not diagnostic; they only help to identify babies at risk and require further testing. In some countries, these tests are mandatory and funded by the Government, but unfortunately in India, it is not yet compulsory.

Newborn Screening (NBS) is a procedure that uses a sample of a newborn baby's blood to screen for potential genetic or medical conditions. A small amount of blood is drawn from the heel of the baby and then placed on a special filter paper. This filter paper is then sent to a screening laboratory along with a form that contains important information about the baby, such as their birth weight, gestational age, date and time of birth, and of sample collection. The hearing test is also conducted using a soft ear plug. 

The number of conditions tested for varies, but generally newborn metabolic screening tests for 31 core disorder types, including phenylketonuria, congenital hypothyroidism, congenital adrenal hyperplasia, galactosemia, sickle cell anemia, and cystic fibrosis. Even if the baby appears normal, it is important for them to undergo NBS to detect any rare or serious conditions that may be present. Although the screening tests only provide preliminary information, they can help doctors determine if more accurate tests are needed.

Trivitron offers an expansive selection of Newborn Screening (NBS) Kits, ranging from modular to fully automated instrumentation, to manual and automated equipment, as well as reagent kits.

Trivitron is a leading provider of Neonatal Screening (NBS) Instruments. They offer a wide range of options, from fully automated instrumentation to manual equipment and reagent kits. Our modular instruments are designed to offer the highest level of accuracy and reliability, while automated systems provide the convenience of easy operation. With the help of their experienced professionals and top-notch products, Trivitron makes sure that the newborn screening process is conducted with the highest level of accuracy and efficiency.

For more details read: When Newborn Screening Should Be Done

The Dangerous Consequences of Neglecting Radiation Protection - Trivitron

Exposure to X-rays can be extremely dangerous, with the potential to not only cause skin damage but also increase the risk of developing cancer. To protect against this, it is essential to use radiation protection products and radiation protection aprons. Radiation protection aprons are used by healthcare practitioners to shield their bodies from X-ray fluoroscopy and other types of harmful radiation beams generated by medical imaging devices during surgery or testing. Those who perform interventional procedures are particularly prone to radiation exposure and should use radiation protection aprons, gloves, thyroid collars, headwear, and glasses to provide full body protection. This can help to reduce the effects of ionizing radiation when working in any imaging environment. Radiation safety education and awareness are key to protecting patients and medical staff. With the recent advances in diagnostic and fluoroscopy, it is important to adhere to guidelines and measures to decrease radiation exposure for doctors, radiologists, and patients. It is essential to ensure that radiation protection products are used appropriately and properly maintained. Regular annual inspections should be carried out to check for the efficacy of personal protective equipment, as even small amounts of radiation can be dangerous. For more information about a wide range of radiation protection aprons and devices, visit Trivitron https://www.trivitron.com
 

Newborn Metabolic Screening Protocols: A Guide

Bringing the infant home is a thrilling experience for parents. The screening of infants for numerous disorders has become mandatory in modern times. Screening an infant guarantees that the infant is devoid of any disorder that is not evident at birth. It also eliminates the risk of any prospective aberration that could develop into a major worry over time. Newborn screening is on the cusp of becoming standard practise as people become more health conscious. The government has also acknowledged its significance and has been crucial in making newborn metabolic screening a mandatory medical procedure. A "walkthrough" will aid in gaining greater understanding of the topic.

Typically, newborn genetic screening begins 48 hours after birth, while the infant is still in the hospital. Any time after the prescribed deadline poses a danger of delayed treatment for a newborn who, by chance, may test positive for any ailment, and a delay in treatment may cause certain treatable disorders to deteriorate into severe irreversible problems. Some hospitals even advise parents, in cooperation with the child's paediatrician, to have the infant undergo a second blood test between 1 and 2 weeks of age.

Optimally, newborn screening is conducted utilising the three approaches listed below:

• Blood tests

• Hearing exam

• Critical Congenital Heart Disease (CCHD) screening

Blood test

Blood or heel testing is the initial stage in the newborn genetic screening procedure. The heel of the infant is pricked and a few drops of blood are drawn. The blood is subsequently transported to a laboratory for examination. In addition, the hospital personnel will collect critical information such as the baby's name and that of its parents, as well as the baby's age, gender, weight, date and time of first feeding, etc. Blood samples are analysed to diagnose a variety of conditions, such as congenital hypothyroidism, sickle cell disease, phenylketonuria, fatty acid metabolism abnormality, etc.

Hearing exam

As the name suggests, this component of the examination helps determine if the infant has a hearing problem or loss. The following tests are commonly used to assess newborns for hearing loss:

The Otoacoustic Emissions Test identifies whether or not specific areas of the infant's ear respond to sound.

Auditory Brain Stem Response Test, which measures the hearing nerve and brain's response to sound.

CCHD testing

CCHD screening is undertaken to rule out the likelihood of critical congenital heart disease in neonates, hence the term. Using an equipment called a "oximeter," a healthcare professional measures the oxygen level in the blood during this examination. Lower oxygen levels in the blood of an infant may indicate structural or behavioural cardiac abnormalities.

Newborn metabolic screening is recommended not only for newborns born in hospitals, but also for those born at home, in adoption centres, or elsewhere. In addition to providing clarity regarding the baby's health, an effective newborn screening assures the baby's safety, health, and happiness in the future.

A newborn screening kit is a set of medical tests that are performed on a newborn baby to identify any potential health problems. The Trivitron's Newborn Screening Kit is a simple, reliable and affordable solution for the early detection of Newborn metabolic screening. Our newborn screening kit is FDA cleared and CE marked.

Were radiation protection aprons not available, what might have happened?

A person can be exposed to radiation if they do not wear protective clothing. Long-term effects, such as DNA abnormalities in sperm or eggs that may be handed down from parent to kid, provide the greatest threat of radiation exposure, despite the fact that the long-term hazards associated with moderate radiation exposure are quite low.

 It's possible that dental X-rays, which contain radiation, are the leading cause of nausea in patients, if a radiation protection apron is not worn. Dental X-rays without a radiation protection apron might cause side effects including fever and headaches.

When is it not necessary to wear the radiation apron?

In extremely unusual cases, dental X-rays may not necessitate the use of a radiation protection apron because there is no known danger of radiation-related illnesses.

If your dentist does not provide you with a radiation protection apron when he or she orders a dental X-ray, you should inquire as to whether or not you will need one.

Dentists can utilise dental X-rays to determine if a problem exists, to avoid further problems, and to choose the best course of treatment for individual dental illnesses. With a wide variety of colours and patterns to choose from, our dental radiation protection aprons and dental technologist radiation protection aprons will add a polished air to your dental radiation safety attire without sacrificing any of its practicality or effectiveness.

Trivitron Healthcare Radiation Protection Aprons

The objective of radiation protection is to prevent the detrimental effects of ionising radiation by minimising needless exposure to radiation. Radiation has become a vital tool for detecting and treating a wide range of disorders in contemporary medicine.

Trivitron Healthcare is the top manufacture, supplier, and distributor of medical equipment, as well as the leading medical technology firm for the production and distribution of radiation protection devices such as Aprons.

To buy radiation protection products Visit https://www.trivitron.com/products/radiation-protection

Visit our previous blog about Radiation Protection Aprons

Introducing the Semi Auto Chemistry Analyzer Labmate Series - Next Generation CI Analyzer

The Clinical Chemistry Analyzer is a commonly used diagnostic tool that analyses blood, plasma, and urine samples to determine the quantitative measurement of Lipids, Substrates, Enzymes, Specific Proteins, and Carbohydrates. The Liver Profile, Kidney Profile, Cardiac Profile, and other common and specialty testing are available under the tests menu. All of these tests are performed in hospitals or as part of routine health checks. Furthermore, the data provide unbiased information that allows for early sickness identification and diagnosis, as well as exposing therapy results and patient prognosis.

Semi Auto Analyzers are now commonly employed in a variety of healthcare settings. The equipment is frequently utilised for research and diagnostic purposes at small and medium-sized hospitals and testing institutes, as well as major institutions such as university hospitals. Semi Auto Analyzers are more appropriate for smaller labs and medical clinics. This is because it can handle less samples concurrently than the fully automated one.

Even though this slows down the overall testing method, it offers for substantial flexibility when the sorts of tests change, necessitating the use of various reagents each time. In any case, a Semi Auto Chemistry Analyzer operates utilising optical techniques and adheres to the concepts of colorimetry, photometry, and absorption.

Trivitron Healthcare Manufacture and wholesale Semi Auto Chemistry Analyzer including Labmate NXT, Plus are working hard to assure timely delivery and adoption in laboratories and clinics.

Dentists should wear radiation protection aprons when taking X-rays

Dental X-rays are an important diagnostic and monitoring tool for oral disorders that require prompt treatment. Most dentists now recommend X-rays at regular intervals for all patients. Dental lead aprons must be worn throughout these treatments to protect patients from X-ray exposure. Furthermore, X-ray treatments can detect a variety of potentially life-threatening tooth and mouth disorders, such as periodontal (gum) disease, some oral cancers, tooth decay, and a variety of other abnormalities. Dental X-rays, on the other hand, pose minor health risks. As a result, a lead apron is frequently required.

Radiation Protection Aprons and X-rays of the Teeth

A radiation protection apron is a type of protective clothing that shields the wearer from radiation exposure during dental X-rays.

The following explains why radiation protection aprons are required during dental X-rays and what may occur if they are not worn.

When taking dental X-rays, why should radiation protection aprons be worn?

As previously stated, during dental X-rays, a radiation protection apron is worn to protect internal organs and other vital body components from radiation exposure.

The radiation protection aprons work by shielding radiation before it enters the body, without interfering with dental X-ray readings. Even though dental X-rays are typically performed in the mouth, radiation exposure may occur in lower body areas; thus, radiation protection aprons are worn during dental X-rays.

Individuals undergoing radiation procedures, as well as staff members, are protected against unnecessary and fatal harm using Trivitron Healthcare radiation protection devices.

How newborn screening is performed in India and what it entails

Newborn screening (NBS) is the technique of screening babies for abnormalities that might cause serious sickness or mortality if not recognized and treated early. Delay or omission in diagnosing an Inborn Error of Metabolism (IEM) or other disorders detectable from birth, such as hypothyroidism, G6PD deficiency, and many more, may result in a significant mental decline in the affected babies. Newborn Metabolic Screening for a variety of metabolic and other abnormalities, allowing for intervention before the onset of symptoms or mental and/or physical disability. Neonatal screening is performed in various developed nations as a means of preventing morbidity and death. Newborn Screening Kits are used by several nations to screen newborns for up to fifty illnesses, depending on the occurrence.

Newborn Screening Kit helps to identify illnesses; it is a coordinated, complete system that includes education, follow-up of aberrant findings and confirmatory testing, diagnosis, treatment, management, periodic outcome assessment, quality assurance, and program evaluation.

Although the actual incidence in India is still under research, it is supposed that hearing problems and congenital cardiac abnormalities have an incidence of roughly 4:1000 and 5:1000, respectively, while the incidence of IEMs is approximately 1:1000. This high occurrence is a result of our country’s high prevalence of consanguinity. Many children acquire mental retardation, learning impairments, autism, dyslexia, behavioral abnormalities, and academic backwardness if undetected and mistreated. The diagnosis, treatment, and management of these affected babies impose a substantial financial and emotional strain on the parents. The most reasonable and cost-effective method of averting such tragedies would be to implement an NBS program that detects the majority of avoidable or curable IEMs and other genetic diseases, if not all of them. Therefore, all metropolitan hospitals in India should perform Newborn Metabolic Screening for at least the most prevalent diseases: Congenital Hypothyroidism, Congenital Adrenal Hyperplasia (CAH), and Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) deficiency. For rural areas, certain centers must be set up in the government hospital itself to cater to the need of the newborns, and they must make it mandatory that after every newborn birth, they must undergo this test.

Common Diseases and Their Prevalence 

Mental retardation’s most prevalent avoidable cause is congenital hypothyroidism. The frequency is 1:2500–2800 live births worldwide. The most prevalent cause of CH, accounting for 75 to 80 % of all cases, is thyroid dysgenesis. The actual incidence of this condition in India is unknown. However, it seems to be much greater than in the rest of the globe. Not only is it the most prevalent avoidable cause of mental retardation, but the treatment cannot be afforded by everyone.

G6PD insufficiency is the most prevalent enzyme deficit, affecting about 400 million individuals worldwide. Additionally, it is the most prevalent genetic condition in India. Although the actual prevalence is unknown, a range of 2-27.9% has been observed by several studies in diverse areas. It is an X-linked recessive condition that manifests with hemolytic anemia and persistent jaundice and causes substantial morbidity and death in children.

In nations such as the United States, Malaysia, Singapore, Taiwan, Hong Kong, the Philippines, the Middle East, and Europe, NBS for G6PD has been effectively applied. Public and pediatric health professionals in India have long recognized NBS for G6PD deficiency. The implementation of a screening program will significantly reduce hospital admissions due to acute hemolysis, hence lowering the need for blood transfusions and dialysis.

PKU, MSUD, homocystinuria, methylmalonic academia, propionic academia, and isovaleric academia are some other common health concerns that be detected by the NBS method. The majority of these conditions are characterized by life-threatening episodes and may leave the afflicted kid with lasting neurological complications if left undiagnosed and untreated.

Need for Universal Newborn Screening Implementation and Proper Execution With Proper Awareness

One must make a note that the Newborn Genetic Screening program’s success is only when there is continuous monitoring of affected infants, even after the test is conducted. There are instances (especially for births in public hospitals) in which the affected infant’s health improves and the parents discontinue treatment without the physicians’ knowledge. This defeats the screening program’s intent. In India, it is difficult to implement newborn screening universally, although increased awareness and initiatives over the last decade have resulted in more newborns getting checked each year.

The success of the current newborn screening program can only be possible with the help of government and awareness campaigns, that aid in making newborn genetic screening a mandatory test and a national program for preventing high infant mortality rates and securing the future health of newborns with initial diagnosis and treatment plans provided by a medical expert.

In addition to Modular & Fully Automated Newborn Screening kit, Trivitron offers reagent kits, manual equipment, and fully automated equipment for newborn screening.

Radiation Protection Products From Trivitron Healthcare

Radiation Protection

The goal of radiation protection is to minimize the harmful effects of ionizing radiation by reducing unnecessary radiation exposure. Radiation has become an indispensable tool in modern medicine for diagnosing and treating a wide variety of diseases.

Trivitron healthcare is the leading manufacturer, supplier and dealer for medical equipment which is also the main medical technology company for manufacturing and supplying of radiation protection products.  

To ensure the safety of the medical practitioner and the patient, every radiation protection devices is made with advanced technology and premium quality raw materials.

Our radiation protection products include the following:

• Radiation Protection Aprons

• Radiation Protection Gloves

• Radiation Protection Shields

• Radiation Protection Apparel

• Radiation Protection Eyewear

All medical radiation protection devices undergo full inspection before being released to the market.

Visual inspection: The process of finding defects in products with the naked eye involves visual inspection. 

Tactile inspection: Using the hands, inspect the entire radiation protection surface for thinning, cracks, lumps, or signs of separation from the sagging or seams.

Radiographic inspection: A final inspection is performed using fluoroscopy or X-rays, depending on the testing method available. Only when visual or manual inspection indicates potential damage is it conducted in order to identify defects that have gone unnoticed in previous inspections. 

Radiation protection apparel and devices from Trivitron Healthcare reduce the risk of unnecessary and fatal harm to individuals undergoing radiation procedures, as well as to the staff.

Universal Newborn Screening | Newborn Screening Kit | Trivitron Healthcare

The Trivitron Healthcare Newborn Screening Kit is a complete solution for newborn metabolic screening. In addition to newborn screening kits, instruments, manual and automated equipment, and reagent kits, we are the complete universal newborn screening system. 

When newborn babies are born, they usually appear healthy and perfect. Newborn metabolic screening is the only way for us to find some potential problems in newborn babies. It identifies certain serious medical conditions in your baby through a special test called the Newborn Metabolic Screen. In order to identify babies who have these disorders early and ensure they receive treatment as soon as possible, the screening aims to detect them before they get sick. 

 In order to provide universal newborn screening kits, Trivitron Healthcare is a leading supplier and manufacturer of health equipment.